SCHEMBL23053207

SCHEMBL23053207

CC(C)C(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 5/20 0.43
▸ NMT2 O60551 4/20 0.43
▸ SIRT6 Q8N6T7 1/20 0.41
▸ SIRT1 Q96EB6 1/20 0.41
▸ MMP1 P03956 3/20 0.39
▸ MMP3 P08254 3/20 0.39
▸ MMP9 P14780 2/20 0.39
▸ FOLH1 Q04609 1/20 0.37
▸ CPB2 Q96IY4 4/20 0.36
▸ FURIN P09958 1/20 0.36
▸ PDF Q9HBH1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24453587 0.89 NMT2 (0.37) NMT1NMT2SIRT6SIRT1MMP1
SCHEMBL23682447 0.89 NMT2 (0.37) NMT1NMT2SIRT6SIRT1MMP1
SCHEMBL24090073 0.88 NMT1 (0.38) NMT1NMT2SIRT6SIRT1MMP1
SCHEMBL14961163 0.84 SIRT6 (0.43) NMT1NMT2SIRT6SIRT1FOLH1
SCHEMBL14961162 0.84 SIRT6 (0.43) NMT1NMT2SIRT6SIRT1FOLH1
SCHEMBL15905676 0.84 SIRT6 (0.42) NMT1NMT2SIRT6SIRT1MMP1
SCHEMBL23758316 0.84 SIRT6 (0.42) NMT1NMT2SIRT6SIRT1MMP1
SCHEMBL24765399 0.83 FOLH1 (0.54) NMT1NMT2SIRT6SIRT1FOLH1
SCHEMBL18823863 0.83 MMP1 (0.48) MMP1MMP3MMP9
SCHEMBL20243562 0.82 SIRT6 (0.44) NMT1NMT2SIRT6SIRT1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11220523-B2 Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein UNIVERSITÄT BASEL (CH) 2022-01-11 — — US disclosed
US-20210061838-A1 CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN UNIVERSITAET BASEL (CH) 2021-03-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11220523-B2 Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein MAG, PMP22, SIGLEC7 NMT1 611/4885NMT2 934/4885SIRT6 3792/4885
US-20210061838-A1 CARBOHYDRATE LIGANDS THAT BIND TO IGM ANTIBODIES AGAINST MYELIN-ASSOCIATED GLYCOPROTEIN MAG, PMP22, SIGLEC7 NMT1 611/4885NMT2 934/4885SIRT6 3792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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