Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954218 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TDP1KDM4ETSHRPRKDC | |
| SCHEMBL10486972 | 0.78 | TTR (0.55) | ALDH1A1TDP1TSHRMAPTHPGD | |
| SCHEMBL5113878 | 0.78 | TTR (0.55) | ALDH1A1TDP1TSHRMAPTHPGD | |
| SCHEMBL27135190 | 0.77 | FBP1 (0.44) | ALDH1A1TDP1MAPTHPGDL3MBTL1 | |
| SCHEMBL27002062 | 0.77 | FBP1 (0.44) | ALDH1A1TDP1MAPTHPGDL3MBTL1 | |
| SCHEMBL11615151 | 0.76 | ALDH1A1 (0.64) | ALDH1A1TDP1KDM4ETSHRPRKDC | |
| SCHEMBL29965864 | 0.76 | MAPT (0.38) | ALDH1A1TDP1KDM4EMAPTHPGD | |
| SCHEMBL3136850 | 0.75 | ALDH1A1 (0.90) | ALDH1A1TDP1KDM4ETSHRPRKDC | |
| SCHEMBL16495093 | 0.75 | ERN1 (0.50) | ALDH1A1TDP1KDM4EMAPTLMNA | |
| SCHEMBL3848297 | 0.74 | KMT2A (0.44) | ALDH1A1TDP1KDM4ETSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642379-A | Phenylalkylamines and methods of making and using the same | 吉尔伽美什制药公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2022204323-A1 | NON-HALLUCINOGENIC ARIADNE ANALOGS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |