SCHEMBL24766342

SCHEMBL24766342

CC(C)C(NC(=O)c1cc2cc(Cl)ccc2o1)C(=O)NCC(=O)N[C@H](C=O)CC1CCNC1=O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADAMTS4 O75173 1/20 0.39
ADAMTS5 Q9UNA0 1/20 0.39
CTSL P07711 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23722351 1.00 ADAMTS4 (0.39) ADAMTS4ADAMTS5CTSLCTSSCTSK
SCHEMBL24766494 1.00 ADAMTS4 (0.39) ADAMTS4ADAMTS5CTSLCTSSCTSK
SCHEMBL24766197 0.91 CTSL (0.40) CTSLCTSS
SCHEMBL24766207 0.90
SCHEMBL23722729 0.90
SCHEMBL23721403 0.85 CTSL (0.49) CTSLCTSSCTSK
SCHEMBL26452015 0.85 CTSL (0.49) CTSLCTSSCTSK
SCHEMBL23723096 0.83 CTSL (0.41) CTSLCTSS
SCHEMBL24766618 0.83 CTSL (0.41) CTSLCTSS
SCHEMBL24766896 0.83 CTSL (0.41) CTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4098653-A1 PHARMACEUTICAL USE OF ALDEHYDE-BASED COMPOUND Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2022-12-07 EP disclosed