Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006851 | 0.67 | SIGMAR1 (0.45) | ACHEBCHEALDH1A1LMNAMEN1 | |
| SCHEMBL29416837 | 0.67 | ACHE (1.00) | ACHEBCHEALDH1A1LMNAMEN1 | |
| SCHEMBL3387188 | 0.67 | ACHE (1.00) | ACHEBCHEALDH1A1LMNAMEN1 | |
| SCHEMBL29766889 | 0.67 | NPC1 (0.41) | ACHEBCHEALDH1A1LMNAMEN1 | |
| SCHEMBL5188925 | 0.67 | NPC1 (0.41) | ACHEBCHEALDH1A1LMNAMEN1 | |
| SCHEMBL7896375 | 0.66 | — | — | |
| SCHEMBL8671479 | 0.66 | POLB (0.42) | ALDH1A1LMNAMEN1KMT2AMAPK1 | |
| SCHEMBL10376168 | 0.66 | PDE3B (0.55) | ACHEBCHEALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL30528596 | 0.66 | NPC1 (0.44) | ACHEBCHEALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL30600296 | 0.66 | MEN1 (1.00) | ACHEBCHEALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841399-B2 | Curable composition comprising dual reactive silane functionality | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-09-23 | — | — | US | disclosed |
| EP-2665788-A1 | CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY | 3M Innovative Properties Company (US) | 2013-11-27 | — | — | EP | disclosed |
| US-20130102728-A1 | CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-25 | — | — | US | disclosed |
| WO-2012003160-A1 | CURABLE COMPOSITION COMPRISING DUAL REACTIVE SILANE FUNCTIONALITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-05 | — | — | WO | disclosed |
| US-4588812-A | Substituted 2,3-dihydro-5H-thiazolo[2,3,-b]quinazoline derivatives | PENNWALT CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| US-4588812-A | Substituted 2,3-dihydro-5H-thiazolo[2,3,-b]quinazoline derivatives | PENNWALT CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| US-4588812-A | Substituted 2,3-dihydro-5H-thiazolo[2,3,-b]quinazoline derivatives | PENNWALT CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |