Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24882529 | 0.86 | TSHR (0.40) | ALDH1A1TSHRPAOXADH1BADH1C | |
| SCHEMBL27414892 | 0.82 | ADH1B (0.42) | ALDH1A1TSHRPAOXADH1BADH1C | |
| SCHEMBL24076531 | 0.82 | TSHR (0.42) | ALDH1A1TSHRPAOXADH1BADH1C | |
| SCHEMBL20902982 | 0.82 | SIGMAR1 (0.42) | ALDH1A1TSHRPAOXADH1BADH1C | |
| SCHEMBL20442863 | 0.82 | — | — | |
| SCHEMBL8642925 | 0.80 | S1PR2 (0.38) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL9263622 | 0.80 | S1PR2 (0.38) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL9179500 | 0.80 | S1PR2 (0.38) | ALDH1A1TSHRADH1BADH1CADH1A | |
| SCHEMBL9261386 | 0.80 | S1PR2 (0.38) | ALDH1A1TSHRADH1BADH1CADH1A | |
| Hydrochloric Acid SCHEMBL8643862 | 0.78 | S1PR2 (0.36) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894416-B1 | FERROPORTIN INHIBITORS AND METHODS OF USE | GLOBAL BLOOD THERAPEUTICS INC (US) | 2022-11-09 | — | — | EP | disclosed |