SCHEMBL24767288

SCHEMBL24767288

Cc1cc(Cc2cc[nH]c2)c[nH]1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.35
HMBS P08397 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16685009 0.75 CALM1 (0.52)
SCHEMBL16020926 0.73 MAPT (0.42) HMBS
SCHEMBL29691485 0.71 DAO (0.42) CAPN1
SCHEMBL28201452 0.71 SMN1; SMN2 (0.38) CAPN1
SCHEMBL4537744 0.70 CALM1 (0.57) CAPN1
Hydrochloric Acid SCHEMBL27693313 0.68 CALM1 (0.55) CAPN1
SCHEMBL30040438 0.68 ALDH1A1 (0.41) CAPN1
SCHEMBL24697676 0.68 ALDH1A1 (0.41) CAPN1
SCHEMBL28597419 0.67 HRH3 (0.40) CAPN1
SCHEMBL28600438 0.67 DAO (0.42) CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4101297-A1 COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES Aerpio Pharmaceuticals, Inc. (US) 2022-12-14 EP disclosed