Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863051 | 0.98 | FAAH (0.43) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL18937755 | 0.98 | FAAH (0.43) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL1069645 | 0.98 | FAAH (0.41) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL6901401 | 0.98 | FAAH (0.41) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL2817480 | 0.96 | L3MBTL1 (0.42) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL6894873 | 0.96 | L3MBTL1 (0.42) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL6897804 | 0.94 | FAAH (0.41) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL6897801 | 0.94 | FAAH (0.41) | FAAHCA2L3MBTL1TSHRMAPK1 | |
| SCHEMBL13013076 | 0.91 | L3MBTL1 (0.41) | CA2L3MBTL1TSHRMAPK1RECQL | |
| SCHEMBL7122564 | 0.91 | FAAH (0.48) | FAAHCA2L3MBTL1THRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744832-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE CORPORATION (US) | 2023-09-05 | — | — | US | disclosed |
| US-20220395506-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | INCYTE CORPORATION | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395506-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | JAK3, JAK1, JAK2 | FAAH 3526/4885CA2 4482/4885L3MBTL1 2309/4885 |
| US-11744832-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | JAK3, JAK1, JAK2 | FAAH 3526/4885CA2 4482/4885L3MBTL1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.