SCHEMBL24767783

SCHEMBL24767783

c1ccc2c(c1)sc1c3cnccc3c3c4ccccc4n(-c4ccncc4)c3c21

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TOP2A P11388 1/20 0.33
▸ MAOA P21397 4/20 0.32
▸ MAOB P27338 4/20 0.32
▸ ACHE P22303 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ GRIN1 Q05586 1/20 0.30
▸ GRIN2A Q12879 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24768833 0.95 ATM (0.36) TOP2AMAOAMAOBACHEKDM4E
SCHEMBL24767791 0.91 ALOX12 (0.34) TOP2AMAOAMAOBACHEKDM4E
SCHEMBL17405830 0.87 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL16275604 0.87 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL24767800 0.87 MAPK10 (0.34) TOP2A
SCHEMBL24767802 0.86 TOP2A (0.34) TOP2A
SCHEMBL24767801 0.86 TOP2A (0.34) TOP2A
SCHEMBL24768830 0.85 CYP17A1 (0.33) TOP2A
SCHEMBL17405484 0.85 KDM4E (0.40) KDM4EATML3MBTL1
SCHEMBL16275595 0.85 KDM4E (0.40) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220251077-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251077-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, SLCO2A1, SLCO2B1 TOP2A 4331/4885MAOA 395/4885MAOB 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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