Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CD69 | Q07108 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PYGB | P11216 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12936319 | 0.90 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL17771655 | 0.90 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL21415430 | 0.89 | MAPK1 (0.51) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL23735602 | 0.89 | MAPK1 (0.56) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL23848966 | 0.86 | MAPK1 (0.61) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL18573708 | 0.85 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL22431361 | 0.85 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL18735615 | 0.85 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL20842452 | 0.85 | ALDH1A1 (0.58) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 | |
| SCHEMBL16393013 | 0.85 | ALDH1A1 (0.55) | ALDH1A1THRBMAPK1CD69SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872147-B1 | METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES | WAVE LIFE SCIENCES LTD (SG) | 2022-12-21 | — | — | EP | disclosed |