Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | NAT1 | P18440 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019004 | 1.00 | PKM (0.47) | PKMHPGDMCL1NAT1KMT2A | |
| SCHEMBL5822509 | 0.79 | PKM (0.57) | PKMHPGDKMT2AALDH1A1GAA | |
| SCHEMBL9908751 | 0.77 | ALDH1A1 (0.65) | PKMHPGDMCL1KMT2AALDH1A1 | |
| SCHEMBL24767797 | 0.77 | PKM (0.46) | PKMHPGDKMT2AALDH1A1LMNA | |
| SCHEMBL31019001 | 0.77 | PKM (0.46) | PKMHPGDKMT2AALDH1A1LMNA | |
| SCHEMBL24768663 | 0.77 | KDM4E (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24768108 | 0.75 | PKM (0.44) | PKMHPGDKMT2AALDH1A1LMNA | |
| SCHEMBL31019005 | 0.75 | PKM (0.44) | PKMHPGDKMT2AALDH1A1LMNA | |
| SCHEMBL6815813 | 0.74 | MCL1 (0.47) | MCL1NAT1ALDH1A1GAAGFER | |
| SCHEMBL1138917 | 0.71 | MEN1 (0.55) | HPGDKMT2AALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529474-A | N-substituted phenyl sulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2022262657-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | 上海璃道医药科技有限公司 | 2022-12-22 | — | — | WO | disclosed |
| CN-115477626-A | N-substituted phenylsulfonamide compound and application thereof | 上海璃道医药科技有限公司 | 2022-12-16 | — | — | CN | disclosed |