Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245691 | 0.84 | OPRL1 (0.42) | OPRL1 | |
| SCHEMBL2473071 | 0.75 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL2476900 | 0.75 | OPRL1 (0.34) | OPRL1 | |
| SCHEMBL31444389 | 0.69 | CHRNB2 (0.50) | OPRL1 | |
| SCHEMBL21516103 | 0.69 | CHRNB2 (0.50) | OPRL1 | |
| SCHEMBL24141816 | 0.67 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL1690157 | 0.66 | OPRL1 (0.55) | OPRL1 | |
| SCHEMBL24141706 | 0.66 | OPRL1 (0.35) | OPRL1 | |
| SCHEMBL24141708 | 0.66 | ASIC3 (0.37) | OPRL1 | |
| SCHEMBL30586977 | 0.66 | OPRL1 (0.43) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374804-A1 | Chemokine receptor binding heterocyclic compounds with enhanced efficacy | Genzyme Corporation (US) | 2011-10-12 | — | — | EP | disclosed |