Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345885 | 0.86 | HDAC1 (0.42) | RECQLCA2MAPK1TP53CA1 | |
| SCHEMBL169862 | 0.83 | CA2 (0.48) | RECQLCA2MAPK1TP53CA1 | |
| SCHEMBL27697229 | 0.81 | CA2 (0.50) | RECQLCA2MAPK1TP53CA1 | |
| SCHEMBL11691872 | 0.81 | RECQL (0.45) | RECQLCA2MAPK1TP53CA1 | |
| SCHEMBL6633304 | 0.79 | RECQL (0.44) | RECQLCA2MAPK1TP53CA1 | |
| SCHEMBL6629876 | 0.79 | RECQL (0.44) | RECQLCA2MAPK1TP53CA1 | |
| SCHEMBL6632177 | 0.78 | RECQL (0.42) | RECQLCA2MAPK1TP53CA1 | |
| SCHEMBL6340106 | 0.78 | CA1 (0.53) | RECQLCA2TP53CA1DPP7 | |
| SCHEMBL27845803 | 0.78 | FOLH1 (0.38) | RECQL | |
| SCHEMBL5166316 | 0.77 | TP53 (0.48) | CA2TP53CA1LCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104865-A1 | ANTI-EGFR ANTIBODY DRUG CONJUGATES | AbbVie Inc. (US) | 2022-12-21 | — | — | EP | disclosed |