Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240268 | 0.92 | TP53 (0.50) | CA2CA1RECQLTP53EPHX1 | |
| SCHEMBL4814530 | 0.92 | TP53 (0.50) | CA2CA1RECQLTP53EPHX1 | |
| SCHEMBL11310381 | 0.92 | TP53 (0.50) | CA2CA1RECQLTP53EPHX1 | |
| SCHEMBL27399020 | 0.87 | HDAC1 (0.41) | CA2CA1RECQLTP53SLC1A3 | |
| SCHEMBL2807679 | 0.83 | CA2 (0.50) | CA2CA1RECQLTP53DPP7 | |
| SCHEMBL2810383 | 0.83 | CA2 (0.50) | CA2CA1RECQLTP53DPP7 | |
| SCHEMBL4811096 | 0.83 | FAAH (0.53) | RECQLTP53CHRM1 | |
| SCHEMBL27368648 | 0.83 | CA1 (0.30) | CA2CA1RECQL | |
| SCHEMBL2808107 | 0.82 | CA2 (0.48) | CA2CA1RECQLTP53DPP7 | |
| SCHEMBL24769578 | 0.81 | RECQL (0.46) | CA2CA1RECQLTP53DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103582642-A | HSP90 inhibitors | SLOAN KETTERING INST CANCER | 2014-02-12 | — | — | CN | claimed |
| CN-101830497-B | Supergravity hydrothermal preparation method of spherical inorganic powder grains | UNIV TONGJI | 2012-06-06 | — | — | CN | claimed |
| CN-102356066-A | Novel 2,6-substituted-3-nitropyridine derivative, method for preparing same, and pharmaceutical composition including same | DONG WHA PHARM CO LTD | 2012-02-15 | — | — | CN | claimed |
| CN-101830497-A | Supergravity hydrothermal preparation method of spherical inorganic powder grains | UNIV TONGJI | 2010-09-15 | — | — | CN | claimed |
| CN-101801967-A | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition for preventing or treating osteoporosis comprising the same | DONG WHA PHARM IND CO LTD | 2010-08-11 | — | — | CN | claimed |
| CN-101379049-A | Novel benzamidine derivatives, process for preparing the same, and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD (KR) | 2009-03-04 | — | — | CN | claimed |
| CN-101010308-A | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD (KR) | 2007-08-01 | — | — | CN | claimed |
| CN-109374889-A | The purposes of the HSP90 inhibitor of label | 索隆-基特林癌症研究协会 | 2019-02-22 | — | — | CN | disclosed |
| CN-104081203-B | Use of labeled HSP90 inhibitors | 索隆-基特林癌症研究协会 | 2018-07-31 | — | — | CN | disclosed |
| CN-104081206-B | The purposes of the HSP90 inhibitor of mark | 索隆-基特林癌症研究协会 | 2017-06-09 | — | — | CN | disclosed |
| CN-104081206-A | Uses of labeled HSP90 inhibitor | SLOAN KETTERING INST CANCER | 2014-10-01 | — | — | CN | disclosed |
| CN-104081203-A | Use of labeled HSP90 inhibitors | SLOAN KETTERING INST CANCER | 2014-10-01 | — | — | CN | disclosed |
| CN-103582642-A | HSP90 inhibitors | SLOAN KETTERING INST CANCER | 2014-02-12 | — | — | CN | disclosed |
| CN-102356066-A | Novel 2,6-substituted-3-nitropyridine derivative, method for preparing same, and pharmaceutical composition including same | DONG WHA PHARM CO LTD | 2012-02-15 | — | — | CN | disclosed |
| CN-101379049-B | Novel benzamidine derivatives, process for preparing the same, and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD | 2012-01-04 | — | — | CN | disclosed |
| CN-101830497-A | Supergravity hydrothermal preparation method of spherical inorganic powder grains | UNIV TONGJI | 2010-09-15 | — | — | CN | disclosed |
| CN-101801967-A | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition for preventing or treating osteoporosis comprising the same | DONG WHA PHARM IND CO LTD | 2010-08-11 | — | — | CN | disclosed |
| CN-101379049-A | Novel benzamidine derivatives, process for preparing the same, and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD (KR) | 2009-03-04 | — | — | CN | disclosed |
| CN-101233435-A | Photosensitive resin composition for liquid crystal display element, color filter using same, method for producing color filter, and liquid crystal display element | FUJIFILM CORP (JP) | 2008-07-30 | — | — | CN | disclosed |
| CN-101010308-A | Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | DONG WHA PHARM IND CO LTD (KR) | 2007-08-01 | — | — | CN | disclosed |