Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963763 | 0.92 | MAPT (0.51) | ALDH1A1MAPTGAAHPGDMAPK1 | |
| SCHEMBL24768598 | 0.85 | NPC1 (0.56) | ALDH1A1MAPTGAAHPGDMEN1 | |
| SCHEMBL24769826 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAHPGDMAPK1 | |
| SCHEMBL29963677 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAHPGDMAPK1 | |
| SCHEMBL29963431 | 0.79 | NPC1 (0.60) | ALDH1A1MAPTGAAHPGDMAPK1 | |
| SCHEMBL38665488 | 0.77 | GAA (0.70) | ALDH1A1MAPTGAAMAPK1MEN1 | |
| SCHEMBL29963543 | 0.75 | GAA (0.56) | ALDH1A1MAPTGAAHPGDMAPK1 | |
| SCHEMBL29274270 | 0.75 | MAPT (0.66) | ALDH1A1MAPTGAAHPGDMAPK1 | |
| SCHEMBL24769834 | 0.74 | GAA (0.56) | ALDH1A1MAPTGAAMAPK1MEN1 | |
| SCHEMBL24769825 | 0.73 | MEN1 (0.49) | ALDH1A1MAPTGAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054608-B1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE MEDICINE (US) | 2026-03-04 | — | — | EP | disclosed |
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2022-12-22 | — | — | US | disclosed |
| EP-4054608-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | Albert Einstein College of Medicine (US) | 2022-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402881-A1 | SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS | PTGER1, PTGIS, PTGIR | ALDH1A1 875/4885MAPT 3079/4885GAA 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.