SCHEMBL24769852

SCHEMBL24769852

O=C(O)CC1CCC(=O)N1Cc1ccc(F)c(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29103291 0.89 P2RX7 (0.53) P2RX7
SCHEMBL31551413 0.89 P2RX7 (0.53) P2RX7
SCHEMBL30158703 0.89 P2RX7 (0.53) P2RX7
SCHEMBL30158646 0.88 P2RX7 (0.42) P2RX7
SCHEMBL29874962 0.86 P2RX7 (0.42) P2RX7
SCHEMBL24768897 0.86 P2RX7 (0.42) P2RX7
SCHEMBL31706819 0.83 KMT2A (0.45) P2RX7
SCHEMBL24810886 0.81 P2RX7 (0.54) P2RX7
SCHEMBL24769849 0.81 P2RX7 (0.54) P2RX7
SCHEMBL31707067 0.81 P2RX7 (0.54) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658770-A1 HERBICIDE RESISTANT PLANTS Syngenta Crop Protection AG (CH) 2025-12-10 EP claimed
WO-2024160989-A1 HERBICIDE RESISTANT PLANTS SYNGENTA CROP PROTECTION AG (CH) 2024-08-08 WO claimed
EP-4658805-A1 METHODS FOR IDENTIFYING HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2025-12-10 EP disclosed
EP-4658770-A1 HERBICIDE RESISTANT PLANTS Syngenta Crop Protection AG (CH) 2025-12-10 EP disclosed
WO-2024160975-A1 METHODS FOR IDENTIFYING HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-08-08 WO disclosed
WO-2024160989-A1 HERBICIDE RESISTANT PLANTS SYNGENTA CROP PROTECTION AG (CH) 2024-08-08 WO disclosed
WO-2022200208-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2022-09-29 WO disclosed