SCHEMBL30158703

SCHEMBL30158703

O=C(O)C[C@H]1CCC(=O)N1Cc1cccc(F)c1F

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 14/20 0.53
PTGDR2 Q9Y5Y4 1/20 0.39
CHRM1 P11229 1/20 0.37
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29103291 1.00 P2RX7 (0.53) P2RX7PTGDR2CHRM1KMT2A
SCHEMBL31551413 1.00 P2RX7 (0.53) P2RX7PTGDR2CHRM1KMT2A
SCHEMBL31706819 0.90 KMT2A (0.45) P2RX7KMT2A
SCHEMBL30157427 0.89 P2RX7 (0.52) P2RX7CHRM1KMT2A
SCHEMBL24769852 0.89 P2RX7 (0.52) P2RX7
SCHEMBL31707067 0.88 P2RX7 (0.54) P2RX7KMT2A
SCHEMBL24769849 0.88 P2RX7 (0.54) P2RX7KMT2A
SCHEMBL24810886 0.88 P2RX7 (0.54) P2RX7KMT2A
SCHEMBL31705751 0.88 P2RX7 (0.43) P2RX7
SCHEMBL29875113 0.88 P2RX7 (0.54) P2RX7KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022268520-A1 USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-12-29 WO disclosed