Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30017436 | 1.00 | POLQ (0.62) | POLQ | |
| SCHEMBL22717500 | 0.83 | POLQ (0.60) | POLQ | |
| SCHEMBL29574407 | 0.83 | POLQ (0.60) | POLQ | |
| SCHEMBL24769234 | 0.83 | POLQ (0.80) | POLQ | |
| SCHEMBL30018176 | 0.83 | POLQ (0.80) | POLQ | |
| SCHEMBL24501180 | 0.82 | POLQ (0.72) | POLQ | |
| SCHEMBL29695079 | 0.82 | POLQ (0.72) | POLQ | |
| SCHEMBL24770167 | 0.81 | POLQ (0.43) | POLQ | |
| SCHEMBL30017759 | 0.81 | POLQ (0.43) | POLQ | |
| SCHEMBL30895795 | 0.80 | POLQ (0.79) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794927-A | O-linked thiadiazolyl compounds as inhibitors of DNA polymerase theta | 伊迪亚生物科学有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2022259204-A1 | O-LINKED THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-12-15 | — | — | WO | disclosed |