Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 18/20 | 0.60 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480350 | 0.93 | TACR3 (0.67) | TACR3TACR2TACR1HSD11B1 | |
| SCHEMBL2480276 | 0.92 | TACR3 (0.54) | TACR3HSD11B1 | |
| SCHEMBL2475976 | 0.92 | TACR3 (0.52) | TACR3HSD11B1 | |
| SCHEMBL2478361 | 0.91 | TACR3 (0.52) | TACR3HSD11B1 | |
| SCHEMBL2478285 | 0.85 | TACR3 (0.54) | TACR3TACR2TACR1HSD11B1 | |
| SCHEMBL2482753 | 0.84 | TACR3 (0.57) | TACR3TACR2TACR1 | |
| SCHEMBL2476664 | 0.84 | TACR3 (0.58) | TACR3HSD11B1 | |
| SCHEMBL2479444 | 0.84 | TACR3 (0.65) | TACR3TACR2TACR1 | |
| SCHEMBL2477331 | 0.83 | TACR3 (0.58) | TACR3TACR2TACR1HSD11B1 | |
| SCHEMBL2478604 | 0.82 | TACR3 (0.52) | TACR3TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | claimed |