Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.76 |
| ▸ | USP2 | O75604 | 11/20 | 0.76 |
| ▸ | KEAP1 | Q14145 | 8/20 | 0.76 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 12/20 | 0.70 |
| ▸ | ATM | Q13315 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 6/20 | 0.51 |
| ▸ | RGS12 | O14924 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482279 | 0.86 | USP2 (1.00) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL29353566 | 0.86 | USP2 (1.00) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL7650466 | 0.82 | KMT2A (0.70) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL22203806 | 0.79 | MEN1 (0.70) | KMT2AUSP2KEAP1NFE2L2KDM4E | |
| SCHEMBL16449728 | 0.78 | KMT2A (0.82) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL28283363 | 0.78 | KMT2A (0.70) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL30553977 | 0.78 | KMT2A (0.70) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL16213260 | 0.77 | KDM4E (0.59) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL3401969 | 0.76 | KMT2A (0.61) | KMT2AUSP2KEAP1NFE2L2MAPT | |
| SCHEMBL29894269 | 0.76 | KMT2A (0.61) | KMT2AUSP2KEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057123-B1 | ANTHRAPYRIDONE COMPOUNDS | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-10-19 | — | — | EP | disclosed |
| US-7812076-B2 | Anthrapyridone compounds | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-10-12 | — | — | US | disclosed |
| EP-2057123-A1 | ANTHRAPYRIDONE COMPOUNDS | Sabic Innovative Plastics IP B.V. (NL) | 2009-05-13 | — | — | EP | disclosed |
| US-20080045634-A1 | ANTHRAPYRIDONE COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2008-02-21 | — | — | US | disclosed |
| WO-2008021694-A1 | ANTHRAPYRIDONE COMPOUNDS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-02-21 | — | — | WO | disclosed |