SCHEMBL3401969

SCHEMBL3401969

O=C1c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C(=O)N1c1ccc(Cl)cc1)c64)C(=O)N(c1ccc(Cl)cc1)C5=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.61
MEN1 O00255 4/20 0.61
NPC1 O15118 3/20 0.60
RAB9A P51151 3/20 0.60
USP2 O75604 2/20 0.60
KEAP1 Q14145 2/20 0.60
NFE2L2 Q16236 2/20 0.60
ATM Q13315 1/20 0.60
POLB P06746 3/20 0.56
APAF1 O14727 1/20 0.56
CA9 Q16790 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
MGLL Q99685 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 2/20 0.43
PGR P06401 2/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29894269 1.00 KMT2A (0.61) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL22203806 0.92 MEN1 (0.70) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL23640397 0.84 KMT2A (0.47) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL18347274 0.81 POLB (0.56) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL9966873 0.81 POLB (0.56) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL16601817 0.81 POLB (0.56) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL24221089 0.81 POLB (0.56) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL9638650 0.81 ALDH1A1 (0.62) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL23640679 0.81 MEN1 (0.44) KMT2AMEN1NPC1RAB9AUSP2
SCHEMBL29726032 0.81 ALDH1A1 (0.60) KMT2AMEN1NPC1RAB9AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 US disclosed
EP-4171500-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER Wella Germany GmbH (DE) 2023-05-03 EP disclosed
US-11324688-B2 Bicomponent composition WELLA INTERNATIONAL OPERATIONS SWI (CH) 2022-05-10 US disclosed
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2022-02-24 US disclosed
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-20 US disclosed
WO-2022002983-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-06 WO disclosed
EP-3890683-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-10-13 EP disclosed
US-20210290518-A1 MULTICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 US disclosed
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 US disclosed
US-20210145726-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2021-05-20 US disclosed
US-20110143273-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-06-16 US disclosed
US-20110143273-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-06-16 US disclosed
EP-2317391-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2011-05-04 EP disclosed
US-20100152339-A1 Graft Copolymer And Compositions Thereof LUBRIZOL LIMITED (GB) 2010-06-17 US disclosed
EP-2150333-A1 GRAFT COPOLYMER AND COMPOSITIONS THEREOF Lubrizol Limited (GB) 2010-02-10 EP disclosed
US-20090104551-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND IMAGE FORMING KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-23 US disclosed
US-20090104551-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND IMAGE FORMING KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-23 US disclosed
WO-2008145613-A1 GRAFT COPOLYMER AND COMPOSITIONS THEREOF LUBRIZOL LIMITED (GB) 2008-12-04 WO disclosed
US-7459256-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-12-02 US disclosed
US-7459256-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES KRT18, ITGA5, FLNA KMT2A 586/4885MEN1 2431/4885NPC1 4829/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK KMT2A 876/4885MEN1 811/4885NPC1 4878/4885
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION CUTA, CD99, PLOD3 KMT2A 648/4885MEN1 10/4885NPC1 4575/4885
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION KRT18, PRKDC, VIM KMT2A 1653/4885MEN1 1309/4885NPC1 4625/4885
US-11324688-B2 Bicomponent composition KRT18, EXOSC10, EXOSC9 KMT2A 1253/4885MEN1 1869/4885NPC1 4580/4885
US-20210290518-A1 MULTICOMPONENT COMPOSITION KRT18, INCENP, IK KMT2A 684/4885MEN1 585/4885NPC1 4839/4885
US-20210145726-A1 BICOMPONENT COMPOSITION KRT18, EXOSC10, EXOSC9 KMT2A 1253/4885MEN1 1869/4885NPC1 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.