Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774769 | 1.00 | ALDH1A1 (0.38) | ALDH1A1ESR2 | |
| SCHEMBL25457110 | 0.79 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL16448473 | 0.79 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL16109561 | 0.78 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL685573 | 0.78 | — | — | |
| SCHEMBL17430832 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL24853942 | 0.77 | ESR2 (0.34) | ESR2 | |
| SCHEMBL5949730 | 0.77 | ESR2 (0.34) | ESR2 | |
| SCHEMBL102075 | 0.74 | THRA (0.38) | ESR2 | |
| SCHEMBL11930045 | 0.73 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159522-A1 | BCL-2 INHIBITOR | BEONE MEDICINES I GMBH (CH) | 2023-05-25 | — | — | US | disclosed |
| US-20220402915-A1 | BCL-2 INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402915-A1 | BCL-2 INHIBITORS | BCL2, BCL2L1, BCL2L2 | ALDH1A1 3125/4885ESR2 473/4885 |
| US-20230159522-A1 | BCL-2 INHIBITOR | BCL2, BCL2A1, BCL2L1 | ALDH1A1 2918/4885ESR2 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.