Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206746 | 0.82 | ADAM17 (0.39) | PARP1MGLLALDH1A1 | |
| SCHEMBL24040316 | 0.78 | PIK3C3 (0.41) | PARP1ALDH1A1 | |
| SCHEMBL2603271 | 0.70 | CXCR4 (0.42) | PARP1ALDH1A1 | |
| SCHEMBL14213448 | 0.70 | CXCR4 (0.42) | PARP1ALDH1A1 | |
| SCHEMBL12643789 | 0.70 | CXCR4 (0.42) | PARP1ALDH1A1 | |
| SCHEMBL26546843 | 0.69 | CXCR4 (0.45) | PARP1ALDH1A1 | |
| SCHEMBL23449294 | 0.69 | PIK3C3 (0.40) | PARP1 | |
| SCHEMBL23768202 | 0.68 | WDR5 (0.39) | — | |
| SCHEMBL28949648 | 0.68 | NPC1 (0.42) | FAAHMGLLALDH1A1 | |
| SCHEMBL8215223 | 0.68 | MAP4K4 (0.38) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402915-A1 | BCL-2 INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402915-A1 | BCL-2 INHIBITORS | BCL2, BCL2L1, BCL2L2 | PARP1 392/4885FAAH 3175/4885MGLL 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.