⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21202663 | 1.00 | — | — | |
| SCHEMBL15964498 | 1.00 | — | — | |
| SCHEMBL12667459 | 0.88 | — | — | |
| SCHEMBL15964497 | 0.87 | — | — | |
| SCHEMBL19577789 | 0.87 | — | — | |
| SCHEMBL24742682 | 0.87 | — | — | |
| SCHEMBL17754508 | 0.85 | — | — | |
| SCHEMBL10005827 | 0.85 | — | — | |
| SCHEMBL24742680 | 0.85 | LGALS8 (0.33) | — | |
| SCHEMBL21202664 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022263569-A1 | ANTISENSE-OLIGONUCLEOTIDES FOR PREVENTION OF KIDNEY DYSFUNCTION PROMOTED BY ENDOTHELIAL DYSFUNCTION BY EPHRIN-B2 SUPPRESSION | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-12-22 | — | — | WO | disclosed |