Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19777495 | 0.88 | LGALS8 (0.33) | LGALS8TLR4LY96 | |
| SCHEMBL26029389 | 0.86 | LGALS8 (0.34) | LGALS8TLR4LY96 | |
| SCHEMBL8059872 | 0.86 | LGALS8 (0.34) | LGALS8TLR4LY96 | |
| SCHEMBL15964498 | 0.85 | — | — | |
| SCHEMBL21202663 | 0.85 | — | — | |
| SCHEMBL24742858 | 0.85 | LGALS8 (0.31) | LGALS8 | |
| SCHEMBL24778340 | 0.85 | — | — | |
| SCHEMBL8607210 | 0.81 | LY96 (0.34) | LGALS8TLR4LY96 | |
| SCHEMBL21202642 | 0.80 | IGF2R (0.31) | LGALS8 | |
| SCHEMBL22736772 | 0.79 | FBP1 (0.37) | LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4105328-A1 | ANTISENSE-OLIGONUCLEOTIDES FOR PREVENTION OF KIDNEY DYSFUNCTION PROMOTED BY ENDOTHELIAL DYSFUNCTION BY EPHRIN-B2 SUPPRESSION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-12-21 | — | — | EP | disclosed |