Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.64 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474374 | 0.89 | HDAC1 (0.65) | HDAC1HDAC2NPC1RAB9AHDAC3 | |
| SCHEMBL2473990 | 0.89 | HDAC1 (0.67) | HDAC1HDAC2NPC1RAB9AHDAC3 | |
| SCHEMBL2474442 | 0.85 | HDAC1 (0.60) | HDAC1HDAC2NPC1RAB9AHDAC3 | |
| SCHEMBL2471256 | 0.85 | UTS2R (0.58) | HDAC1UTS2RHDAC2HDAC3 | |
| SCHEMBL2474635 | 0.84 | UTS2R (0.50) | HDAC1UTS2RHDAC2NPC1RAB9A | |
| SCHEMBL2478586 | 0.84 | HDAC1 (0.60) | HDAC1HDAC2NPC1RAB9AHDAC3 | |
| SCHEMBL2474090 | 0.84 | UTS2R (0.52) | HDAC1UTS2RHDAC2NPC1RAB9A | |
| SCHEMBL2474114 | 0.84 | UTS2R (0.54) | HDAC1UTS2R | |
| SCHEMBL2480482 | 0.83 | UTS2R (0.55) | HDAC1UTS2RHDAC2HDAC3 | |
| SCHEMBL3835404 | 0.83 | HDAC1 (0.59) | HDAC1UTS2RHDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | claimed |