Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847393 | 0.82 | HTR2A (0.71) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| SCHEMBL27585564 | 0.79 | HTR2A (0.60) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| SCHEMBL21169643 | 0.78 | HTR2A (0.62) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Roluperidone SCHEMBL5252391 | 0.78 | HTR2A (1.00) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| SCHEMBL4466754 | 0.78 | L3MBTL1 (0.56) | ALDH1A1HPGDLMNAL3MBTL1PDE6D | |
| SCHEMBL5693198 | 0.78 | L3MBTL1 (0.56) | ALDH1A1HPGDLMNAL3MBTL1PDE6D | |
| Roluperidone SCHEMBL5248131 | 0.77 | HTR2A (0.98) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Hydrochloric Acid SCHEMBL27565675 | 0.77 | HTR2A (0.61) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| SCHEMBL5250853 | 0.77 | HTR2A (0.83) | HTR2AHTR1ATMEM97HTR2CKCNH2 | |
| Roluperidone SCHEMBL5253902 | 0.76 | HTR2A (0.96) | HTR2AHTR1ATMEM97HTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401368-A1 | GASTRO-RESISTANT CONTROLLED RELEASE ORAL DOSAGE FORMS | MINERVA NEUROSCIENCES, INC. | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220401368-A1 | GASTRO-RESISTANT CONTROLLED RELEASE ORAL DOSAGE FORMS | CYP2D6, UGT1A3, UGT1A6 | HTR2A 400/4885HTR1A 238/4885TMEM97 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.