Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.69 |
| ▸ | CASP2 | P42575 | 1/20 | 0.66 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.48 |
| ▸ | KDM5A | P29375 | 2/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130593 | 0.92 | DNM1 (0.76) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL30130591 | 0.92 | DNM1 (0.76) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL25413301 | 0.92 | DNM1 (0.81) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL9549506 | 0.92 | DNM1 (0.81) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL3884774 | 0.92 | DNM1 (0.81) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL25413209 | 0.92 | DNM1 (0.81) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL9487043 | 0.90 | DNM1 (0.78) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL9549486 | 0.90 | CASP2 (0.76) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL9549382 | 0.90 | DNM1 (0.78) | DNM1CASP2NAAAFAAHEPHX2 | |
| SCHEMBL31325297 | 0.90 | DNM1 (0.73) | DNM1CASP2NAAAFAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261235-A1 | NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |