Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320779 | 0.87 | THRB (0.48) | THRBTSHRGAAL3MBTL1ALDH1A1 | |
| SCHEMBL9506717 | 0.83 | THRB (0.46) | SRD5A2THRBTSHRPOLBTDP1 | |
| SCHEMBL10868118 | 0.81 | THRB (0.44) | THRBTSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL4578981 | 0.78 | THRB (0.47) | THRBTSHRTDP1ALDH1A1TP53 | |
| SCHEMBL28626780 | 0.78 | THRB (0.47) | THRBTSHRGAAPOLBTDP1 | |
| SCHEMBL1009964 | 0.78 | GAA (0.49) | SRD5A2THRBTSHRGAATDP1 | |
| SCHEMBL10892162 | 0.77 | THRB (0.46) | THRBTSHRGAAPOLBTDP1 | |
| SCHEMBL10894868 | 0.77 | THRB (0.46) | THRBTSHRGAAPOLBTDP1 | |
| SCHEMBL6283584 | 0.75 | DCLRE1B (0.54) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10893111 | 0.75 | POLB (0.47) | THRBTSHRGAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376550-A1 | MODIFIED POLYVINYLLACTAMS | BASF SE (DE) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010066613-A1 | MODIFIED POLYVINYLLACTAMS | BASF SE (DE) | 2010-06-17 | — | — | WO | disclosed |