SCHEMBL2478286

SCHEMBL2478286

OB(O)c1ccc2cc(-c3cc4ccc5ccccc5c4c4ccccc34)ccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
GPR84 Q9NQS5 1/20 0.38
GSTP1 P09211 1/20 0.38
MGLL Q99685 2/20 0.37
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
ALDH1A1 P00352 2/20 0.34
ESR2 Q92731 2/20 0.34
ESR1 P03372 1/20 0.34
CYP1A2 P05177 2/20 0.33
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2902991 0.89 CA1 (0.46) CA1CA2MGLLKDM4EMEN1
SCHEMBL1094143 0.86 CA1 (0.59) CA1CA2GPR84GSTP1MGLL
SCHEMBL31376292 0.86 CA1 (0.59) CA1CA2GPR84GSTP1MGLL
SCHEMBL12025740 0.86 CA1 (0.51) CA1CA2GPR84GSTP1MGLL
SCHEMBL2165047 0.83 CA1 (0.59) CA1CA2GSTP1MGLLHDAC4
SCHEMBL2903602 0.82 GSTP1 (0.46) GPR84GSTP1KDM4EMEN1KMT2A
SCHEMBL2473747 0.82 CA1 (0.58) CA1CA2GPR84GSTP1MGLL
SCHEMBL28909290 0.81 CA1 (0.66) CA1CA2MGLLALDH1A1CYP1A2
SCHEMBL30959845 0.79 CA1 (0.62) CA1CA2MGLLALDH1A1CYP1A2
SCHEMBL12144584 0.77 CA1 (0.59) CA1CA2MGLLALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2713415-B1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2018-12-19 EP disclosed
US-8940412-B2 Material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-8940412-B2 Material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-8940412-B2 Material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-01-27 US disclosed
US-20110315965-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-12-29 US disclosed
CN-102265424-A Material for organic electroluminescent element and organic electroluminescent element 2011-11-30 CN disclosed
US-8039127-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US disclosed
US-8039129-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US disclosed
EP-2372803-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2011-10-05 EP disclosed
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100253211-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110315965-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, TERF2, BPTF CA1 2309/4885CA2 2843/4885GPR84 4594/4885
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, LEF1, LIMK1 CA1 3843/4885CA2 3319/4885GPR84 4193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.