Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LOX | P28300 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233450 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1CHKACHRM5TERT | |
| SCHEMBL30262293 | 0.72 | LOXL2 (0.52) | LOXL2KDM4ELOXCHKANOTUM | |
| SCHEMBL21849250 | 0.72 | ALDH1A1 (0.50) | LOXL2KDM4EALDH1A1CHKACHRM5 | |
| SCHEMBL29419408 | 0.72 | ALDH1A1 (0.50) | LOXL2KDM4EALDH1A1CHKACHRM5 | |
| SCHEMBL132321 | 0.72 | LOXL2 (0.52) | LOXL2KDM4ELOXCHKANOTUM | |
| SCHEMBL31401539 | 0.72 | LOXL2 (0.47) | LOXL2LOXCHKANOTUMIDO1 | |
| SCHEMBL196641 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1CHKACHRM5TERT | |
| SCHEMBL2642373 | 0.70 | LOXL2 (0.53) | LOXL2LOXCHKANOTUMIDO1 | |
| SCHEMBL1857798 | 0.70 | UHRF1 (0.52) | KDM4EALDH1A1CHKACHRM5TERT | |
| SCHEMBL30328281 | 0.70 | LOXL2 (0.53) | LOXL2KDM4ELOXCHKANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |