Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13382908 | 0.93 | SMYD3 (0.43) | CYP11B1CYP11B2SMYD3XIAPBIRC2 | |
| SCHEMBL23432583 | 0.82 | CYP11B1 (0.43) | CYP11B1CYP11B2SMYD3XIAPBIRC2 | |
| SCHEMBL30509174 | 0.77 | EPHX2 (0.51) | CYP11B1CYP11B2SMYD3POLBMAPT | |
| SCHEMBL12672111 | 0.77 | EPHX2 (0.51) | CYP11B1CYP11B2SMYD3POLBMAPT | |
| SCHEMBL23346087 | 0.75 | — | — | |
| SCHEMBL12207050 | 0.74 | BRD4 (0.47) | CYP11B1CYP11B2SMYD3 | |
| SCHEMBL1119397 | 0.74 | CMA1 (0.56) | CYP11B1CYP11B2SMYD3 | |
| SCHEMBL12361998 | 0.74 | AHR (0.56) | CYP11B1CYP11B2SMYD3PDE3BPDE3A | |
| SCHEMBL15521357 | 0.74 | AHR (0.56) | SMYD3PKMKIF11CRBN | |
| SCHEMBL29036203 | 0.74 | PDE3B (0.57) | CYP11B1CYP11B2SMYD3POLBPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |