Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | CDC42BPB | Q9Y5S2 | 2/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24783753 | 0.81 | UCHL1 (0.36) | UCHL1ROCK2LRRK2AKT1AKT2 | |
| SCHEMBL24783739 | 0.79 | S1PR1 (0.43) | UCHL1S1PR1S1PR3LRRK2SCN9A | |
| SCHEMBL25124543 | 0.77 | CYP17A1 (0.40) | UCHL1ROCK2LRRK2AKT1AKT2 | |
| SCHEMBL2625808 | 0.77 | HTR2C (0.47) | UCHL1S1PR1S1PR3 | |
| SCHEMBL25124593 | 0.77 | S1PR1 (0.43) | UCHL1S1PR1S1PR3LRRK2 | |
| SCHEMBL23055771 | 0.77 | GRM5 (0.45) | ADRA1AS1PR1S1PR3PDK2 | |
| SCHEMBL25124401 | 0.76 | ROCK2 (0.41) | ROCK2LRRK2P2RX7AKT1AKT2 | |
| SCHEMBL23639223 | 0.76 | UCHL1 (0.46) | UCHL1S1PR1S1PR3LRRK2AKT1 | |
| SCHEMBL23055375 | 0.75 | UCHL1 (0.50) | UCHL1S1PR1S1PR3ROCK2LRRK2 | |
| SCHEMBL25124392 | 0.75 | UCHL1 (0.50) | UCHL1ADRA1AAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2023-04-13 | — | — | US | disclosed |
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | MAPT, PSEN1, PSEN2 | UCHL1 1759/4885ADRA1D 1897/4885ADRA1A 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.