Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25124515 | 0.81 | FABP6 (0.47) | FABP6GSK3BMKNK1TYK2AR | |
| SCHEMBL18090602 | 0.78 | FABP6 (0.50) | FABP6GSK3BMAPTALDH1A1GAA | |
| SCHEMBL25124516 | 0.77 | PARP11 (0.49) | GSK3BDDB1CRBNMKNK1ALDH1A1 | |
| SCHEMBL31638458 | 0.77 | ALDH1A1 (0.57) | FABP6GSK3BCYP1A2CYP2C19NPSR1 | |
| SCHEMBL10274616 | 0.76 | ALDH1A1 (0.56) | FABP6GSK3BMAPTALDH1A1GAA | |
| SCHEMBL23432222 | 0.75 | PARP10 (0.58) | MKNK1PARP10PARP11 | |
| SCHEMBL12078170 | 0.73 | PARP10 (0.54) | FABP6GSK3BMAPTALDH1A1GAA | |
| SCHEMBL2994247 | 0.73 | MAOA (0.58) | FABP6GSK3BMAPTALDH1A1 | |
| SCHEMBL1887176 | 0.73 | FABP6 (0.77) | FABP6GSK3BJAK2NTRK1PARP10 | |
| SCHEMBL2061574 | 0.73 | FABP6 (0.54) | FABP6GSK3BMKNK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104861-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-21 | — | — | EP | disclosed |