Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27057334 | 0.89 | ADRB2 (0.44) | ADRB2HTR1BNR2E1ALDH1A1KDM4E | |
| SCHEMBL23787476 | 0.86 | KDM4E (0.37) | ADRB2HTR1BKDM4ETDP1MEN1 | |
| SCHEMBL22548882 | 0.86 | ADRB2 (0.43) | ADRB2HTR1BNR2E1ALDH1A1KDM4E | |
| SCHEMBL22930111 | 0.86 | ADRB2 (0.43) | ADRB2HTR1BNR2E1ALDH1A1KDM4E | |
| SCHEMBL28765742 | 0.81 | KDM4E (0.39) | ADRB2HTR1BNR2E1ALDH1A1KDM4E | |
| SCHEMBL14442979 | 0.80 | TSHR (0.44) | ADRB2HTR1BNR2E1ALDH1A1MAPT | |
| SCHEMBL15510790 | 0.80 | SLC6A2 (0.40) | ADRB2HTR1BNR2E1MAPTHSD17B10 | |
| SCHEMBL23807055 | 0.78 | SLC6A2 (0.39) | ADRB2HTR1BNR2E1MAPTHSD17B10 | |
| SCHEMBL23075826 | 0.78 | ADRB2 (0.42) | ADRB2HTR1BNR2E1ALDH1A1KDM4E | |
| SCHEMBL25479416 | 0.78 | TSHR (0.41) | ADRB2HTR1BNR2E1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357180-A1 | DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| US-11524949-B2 | Degraders and Degrons for targeted protein degradation | C4 THERAPEUTICS, INC. (US) | 2022-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357180-A1 | DEGRADERS AND DEGRONS FOR TARGETED PROTEIN DEGRADATION | STUB1, MDM2, USP30 | ADRB2 4295/4885HTR1B 3069/4885NR2E1 1594/4885 |
| US-11524949-B2 | Degraders and Degrons for targeted protein degradation | STUB1, MDM2, USP30 | ADRB2 4295/4885HTR1B 3069/4885NR2E1 1594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.