Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103103 | 1.00 | KDM1A (0.55) | KDM1ANPC1TP53PKMRAB9A | |
| SCHEMBL30103108 | 0.89 | CYP17A1 (0.50) | KDM1ANPC1TP53PKMRAB9A | |
| SCHEMBL24785848 | 0.89 | CYP17A1 (0.50) | KDM1ANPC1TP53PKMRAB9A | |
| SCHEMBL30103063 | 0.86 | KDM1A (0.55) | KDM1ANPC1TP53PKMRAB9A | |
| SCHEMBL30103043 | 0.86 | KDM1A (0.55) | KDM1ANPC1TP53PKMRAB9A | |
| SCHEMBL24785040 | 0.86 | KDM1A (0.55) | KDM1ANPC1TP53PKMRAB9A | |
| SCHEMBL24785077 | 0.83 | KDM1A (0.42) | KDM1AFYNPHF8CYP17A1PAX8 | |
| SCHEMBL30103141 | 0.83 | KDM1A (0.42) | KDM1AFYNPHF8CYP17A1PAX8 | |
| SCHEMBL3162853 | 0.77 | CA2 (0.45) | SMN1; SMN2 | |
| SCHEMBL30103064 | 0.75 | CYP17A1 (0.50) | KDM1ANPC1TP53PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |