Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103063 | 0.89 | KDM1A (0.55) | FYNNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30103043 | 0.89 | KDM1A (0.55) | FYNNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL24785040 | 0.89 | KDM1A (0.55) | FYNNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30103108 | 0.86 | CYP17A1 (0.50) | CYP17A1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24785848 | 0.86 | CYP17A1 (0.50) | CYP17A1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9806844 | 0.85 | SMN1; SMN2 (0.64) | CYP17A1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24785367 | 0.83 | PDGFRB (0.51) | CYP17A1FYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8382053 | 0.82 | CYP11B1 (0.57) | CYP17A1FYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16440913 | 0.82 | CASP3 (0.64) | CYP17A1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12987609 | 0.81 | ALDH1A1 (0.52) | CYP17A1FYNNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |