SCHEMBL24785829 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	KDM1A	O60341	1/20	0.49

▸	PHF8	Q9UPP1	1/20	0.40

▸	GRM5	P41594	1/20	0.40

▸	FYN	P06241	4/20	0.39

▸	ALOX5AP	P20292	1/20	0.38

▸	FEN1	P39748	1/20	0.38

▸	GRK6	P43250	1/20	0.38

▸	TDO2	P48775	1/20	0.38

▸	PAX8	Q06710	1/20	0.38

▸	ROCK2	O75116	1/20	0.37

▸	PDGFRB	P09619	1/20	0.37

▸	PDGFRA	P16234	1/20	0.37

▸	PTGS2	P35354	2/20	0.37

▸	CD274	Q9NZQ7	1/20	0.36

▸	OXTR	P30559	1/20	0.36

▸	AVPR1A	P37288	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30103087	1.00	KDM1A (0.49)	KDM1APHF8GRM5FYNALOX5AP
SCHEMBL24785816	0.89	NPC1 (0.47)	FYNALOX5APFEN1TDO2PDGFRB
SCHEMBL30103021	0.89	NPC1 (0.47)	FYNALOX5APFEN1TDO2PDGFRB
SCHEMBL30103062	0.86	KDM1A (0.49)	KDM1APHF8GRM5FYNALOX5AP
SCHEMBL24785826	0.86	KDM1A (0.49)	KDM1APHF8GRM5FYNALOX5AP
SCHEMBL24784615	0.83	GRM5 (0.46)	KDM1AGRM5FYNGRK6PAX8
SCHEMBL30103063	0.81	KDM1A (0.55)	KDM1AFYNROCK2
SCHEMBL24785040	0.81	KDM1A (0.55)	KDM1AFYNROCK2
SCHEMBL30103043	0.81	KDM1A (0.55)	KDM1AFYNROCK2
SCHEMBL24785814	0.75	ALDH1A1 (0.47)	ALOX5APFEN1TDO2PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022257960-A1	BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES	武汉人福创新药物研发中心有限公司	2022-12-15	—	—	WO	disclosed