Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785826 | 1.00 | KDM1A (0.49) | KDM1APHF8GRM5KDM4EALDH1A1 | |
| SCHEMBL24785814 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1PTGS2ALOX5AP | |
| SCHEMBL30103128 | 0.89 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1PTGS2ALOX5AP | |
| SCHEMBL30103087 | 0.86 | KDM1A (0.49) | KDM1APHF8GRM5PTGS2ALOX5AP | |
| SCHEMBL24785829 | 0.86 | KDM1A (0.49) | KDM1APHF8GRM5PTGS2ALOX5AP | |
| SCHEMBL24784623 | 0.83 | GRM5 (0.46) | KDM1AGRM5KDM4EALDH1A1TDP1 | |
| SCHEMBL30103001 | 0.83 | GRM5 (0.46) | KDM1AGRM5KDM4EALDH1A1TDP1 | |
| SCHEMBL24785054 | 0.76 | GRIN2B (0.38) | KDM1APHF8GRM5ALDH1A1PTGS2 | |
| SCHEMBL24785816 | 0.75 | NPC1 (0.47) | KDM4EALDH1A1PTGS2ALOX5APFEN1 | |
| SCHEMBL30103021 | 0.75 | NPC1 (0.47) | KDM4EALDH1A1PTGS2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |