Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 3/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211511 | 0.83 | NOS1 (0.43) | METAP2METAP1MARS1RNPEPCTSS | |
| SCHEMBL11119448 | 0.83 | NOS1 (0.43) | METAP2METAP1MARS1RNPEPCTSS | |
| SCHEMBL7157725 | 0.83 | NOS1 (0.43) | METAP2METAP1MARS1RNPEPCTSS | |
| Hydrochloric Acid SCHEMBL5211496 | 0.81 | NOS1 (0.42) | METAP2METAP1MARS1RNPEPCTSS | |
| Hydrochloric Acid SCHEMBL918798 | 0.81 | NOS1 (0.42) | METAP2METAP1MARS1RNPEPCTSS | |
| SCHEMBL27863494 | 0.77 | NOS1 (0.41) | METAP2METAP1MARS1RNPEPCYP2C19 | |
| SCHEMBL162031 | 0.75 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPBHMT | |
| SCHEMBL20996747 | 0.75 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPBHMT | |
| SCHEMBL6045793 | 0.75 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPBHMT | |
| SCHEMBL5617582 | 0.75 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPBHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220403297-A1 | PRO-BENEFIT-AGENT COMPOUNDS WITH CARBON/NITROGEN BONDS | THE PROCTER & GAMBLE COMPANY | 2022-12-22 | — | — | US | disclosed |