SCHEMBL2478747

SCHEMBL2478747

C=CCCc1ccc(-c2ccc(-c3ccc(CC)cc3)cc2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.39
CHKA P35790 1/20 0.36
TAAR1 Q96RJ0 1/20 0.33
GCGR P47871 1/20 0.33
MAPK14 Q16539 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
DGAT1 O75907 1/20 0.32
SOAT1 P35610 1/20 0.32
HTR2A P28223 1/20 0.32
GRM2 Q14416 1/20 0.32
GRIA4 P48058 1/20 0.32
FAAH O00519 1/20 0.31
MAPT P10636 1/20 0.31
APP P05067 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999856 0.93 RARB (0.40) RARBCHKATAAR1GCGRMAPK14
SCHEMBL12760546 0.93 RARB (0.40) RARBCHKATAAR1GCGRMAPK14
SCHEMBL13253194 0.91 RARB (0.39) RARBCHKATAAR1DGAT1SOAT1
SCHEMBL13253197 0.88 BACE1 (0.42) RARBCHKATAAR1DGAT1SOAT1
SCHEMBL18540247 0.88 RARB (0.39) RARBCHKATAAR1DGAT1SOAT1
SCHEMBL2477723 0.85 RARB (0.41) RARBCHKATAAR1GCGRMAPK14
SCHEMBL18540268 0.85 RARB (0.46) RARBCHKAMAPTCYP3A4
SCHEMBL18540027 0.84 TAAR1 (0.39) RARBCHKATAAR1GRM2CYP3A4
SCHEMBL15180193 0.84 RARB (0.43) RARBCHKATAAR1MAPT
SCHEMBL16789601 0.84 RARB (0.43) RARBCHKATAAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1970362-B1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2011-10-12 EP disclosed
EP-1970362-B1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2011-10-12 EP disclosed
US-7749403-B2 Monofluorinated terphenyl compound having alkenyl, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2010-07-06 US disclosed
US-7749403-B2 Monofluorinated terphenyl compound having alkenyl, liquid crystal composition, and liquid crystal display device CHISSO CORPORATION (JP) 2010-07-06 US disclosed
US-7597944-B2 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2009-10-06 US disclosed
US-7597944-B2 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2009-10-06 US disclosed
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2009-08-20 US disclosed
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2009-08-20 US disclosed
US-20080246001-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2008-10-09 US disclosed
US-20080246001-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2008-10-09 US disclosed
EP-1970362-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2008-09-17 EP disclosed
EP-1970362-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090206300-A1 MONOFLUORINATED TERPHENYL COMPOUND HAVING ALKENYL, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, FZD7, HTR1D RARB 3441/4885CHKA 2843/4885TAAR1 302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.