Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264893 | 0.92 | OPRK1 (0.35) | LMNAMEN1KMT2AOPRK1CA1 | |
| SCHEMBL23961617 | 0.89 | CA12 (0.36) | LMNAOPRK1CA1CA2CA12 | |
| SCHEMBL20402344 | 0.89 | CA12 (0.36) | LMNAOPRK1CA1CA2CA12 | |
| SCHEMBL18909059 | 0.86 | CA12 (0.34) | LMNAMEN1KMT2AOPRK1CA1 | |
| SCHEMBL17722949 | 0.86 | CA12 (0.34) | LMNAMEN1KMT2AOPRK1CA1 | |
| SCHEMBL17815411 | 0.86 | CA12 (0.34) | LMNAMEN1KMT2AOPRK1CA1 | |
| SCHEMBL19705582 | 0.86 | CA12 (0.34) | LMNAMEN1KMT2AOPRK1CA1 | |
| SCHEMBL23789199 | 0.86 | CA12 (0.34) | LMNAMEN1KMT2AOPRK1CA1 | |
| SCHEMBL24087858 | 0.86 | OPRK1 (0.35) | LMNAOPRK1CA1CA2CA12 | |
| SCHEMBL21008369 | 0.85 | CA12 (0.33) | LMNAMEN1KMT2AOPRK1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870234-B1 | ANTIBODY DRUG CONJUGATES COMPRISING ECTEINASCIDIN DERIVATIVES | PHARMA MAR SA (ES) | 2022-12-21 | — | — | EP | disclosed |