Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GLI1 | P08151 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1596519 | 0.93 | EPHX1 (0.59) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL16801898 | 0.86 | MAPK1 (0.47) | EPHX1PKM | |
| SCHEMBL2261600 | 0.86 | MAPK1 (0.47) | EPHX1PKM | |
| SCHEMBL11438411 | 0.82 | PKM (0.53) | EPHX1PKMEPHX2 | |
| SCHEMBL28231320 | 0.81 | EPHX1 (0.45) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL28231346 | 0.81 | EPHX1 (0.45) | EPHX1POLBGNAI3GNAO1GNAI1 | |
| SCHEMBL2869853 | 0.81 | EPHX1 (0.56) | EPHX1PKMEPHX2 | |
| SCHEMBL9451038 | 0.81 | EPHX1 (0.56) | EPHX1PKMEPHX2 | |
| SCHEMBL135838 | 0.81 | EPHX1 (0.56) | EPHX1PKMEPHX2 | |
| Hydrochloric Acid SCHEMBL28827123 | 0.80 | EPHX1 (0.44) | EPHX1POLBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261210-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |