Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24790497 | 0.95 | PIK3CD (0.33) | PIK3CDTMPRSS2CSNK2A2CSNK2A1 | |
| SCHEMBL24789794 | 0.86 | PIK3CD (0.34) | PIK3CDTMPRSS2 | |
| SCHEMBL25916628 | 0.86 | TMPRSS2 (0.32) | PIK3CDTMPRSS2 | |
| SCHEMBL29566128 | 0.84 | TMPRSS2 (0.32) | PIK3CDTMPRSS2 | |
| SCHEMBL27121333 | 0.84 | TMPRSS2 (0.32) | PIK3CDTMPRSS2 | |
| SCHEMBL25608337 | 0.83 | MGLL (0.38) | TMPRSS2 | |
| SCHEMBL26399290 | 0.82 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL26399270 | 0.82 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL24790990 | 0.82 | TMPRSS2 (0.30) | PIK3CDTMPRSS2 | |
| SCHEMBL26399140 | 0.82 | PIK3CD (0.33) | PIK3CDTMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |