Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.33 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26399270 | 0.97 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL26399290 | 0.97 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL26399191 | 0.91 | AXL (0.32) | TMPRSS2 | |
| SCHEMBL26399178 | 0.89 | TMPRSS2 (0.32) | PIK3CDTMPRSS2 | |
| SCHEMBL24790990 | 0.89 | TMPRSS2 (0.30) | PIK3CDTMPRSS2 | |
| SCHEMBL24789794 | 0.88 | PIK3CD (0.34) | PIK3CDTMPRSS2 | |
| SCHEMBL26399166 | 0.87 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL24790497 | 0.86 | PIK3CD (0.33) | PIK3CDTMPRSS2 | |
| SCHEMBL29566128 | 0.86 | TMPRSS2 (0.32) | PIK3CDTMPRSS2 | |
| SCHEMBL26320604 | 0.86 | PIK3CD (0.31) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780844-B2 | Compounds and methods for treatment of viral infections | GILEAD SCIENCES, INC. (US) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780844-B2 | Compounds and methods for treatment of viral infections | HAVCR2, EIF2AK2, OAT | PIK3CD 4574/4885POLRMT 16/4885TMPRSS2 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.