Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460884 | 0.85 | KDM1A (0.39) | KDM1AHTR2AHTR2CHTR2BUSP30 | |
| SCHEMBL15397624 | 0.73 | KDM1A (0.41) | KDM1AHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL556475 | 0.72 | HTR2A (0.44) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL556953 | 0.72 | KDM1A (0.37) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL2458434 | 0.72 | FFAR2 (0.39) | KDM1A | |
| SCHEMBL3810985 | 0.71 | KDM1A (0.40) | KDM1AUSP30ABCB1ABCG2 | |
| SCHEMBL12979087 | 0.71 | KDM1A (0.40) | KDM1AUSP30ABCB1ABCG2 | |
| SCHEMBL18272446 | 0.70 | FFAR1 (0.50) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL12915852 | 0.70 | FFAR1 (0.50) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL248384 | 0.70 | FFAR1 (0.50) | KDM1AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367785-A1 | NOVEL 3-PHENYL-AZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-09-28 | — | — | EP | disclosed |
| EP-2367786-A1 | NOVEL 1 -ALKYL- 3 -HYDROXY- 3 -PHENYLAZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-09-28 | — | — | EP | disclosed |