Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | USP5 | P45974 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12979087 | 1.00 | KDM1A (0.40) | KDM1ASLC6A9FFAR2RIPK1USP5 | |
| SCHEMBL582066 | 0.85 | SLC6A9 (0.40) | SLC6A9FFAR2 | |
| SCHEMBL2705801 | 0.84 | CCNC (0.39) | SLC6A9RIPK1 | |
| SCHEMBL6126585 | 0.83 | USP30 (0.40) | KDM1ASLC6A9FFAR2RIPK1USP5 | |
| SCHEMBL2706713 | 0.83 | USP30 (0.40) | KDM1ASLC6A9FFAR2RIPK1USP5 | |
| SCHEMBL2708043 | 0.83 | USP30 (0.40) | KDM1ASLC6A9FFAR2RIPK1USP5 | |
| SCHEMBL6126899 | 0.82 | USP30 (0.39) | KDM1ASLC6A9FFAR2RIPK1USP5 | |
| SCHEMBL6121459 | 0.82 | USP30 (0.39) | KDM1ASLC6A9FFAR2RIPK1USP5 | |
| SCHEMBL6121112 | 0.80 | HCRTR2 (0.39) | SLC6A9FFAR2RIPK1USP5HDAC6 | |
| SCHEMBL16401399 | 0.79 | RIPK1 (0.50) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114978-A1 | RENIN INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-10-07 | — | — | WO | disclosed |