SCHEMBL24795945

SCHEMBL24795945

CC(C)(C)C1CCC2C(=O)N(CCNC(=O)CSCC(=O)NC3CCCC3)C(=O)C2C1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.41
▸ HPGD P15428 3/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ LMNA P02545 2/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ GAA P10253 3/20 0.36
▸ POLB P06746 2/20 0.36
▸ EPHX1 P07099 1/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ USP2 O75604 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ NOD2 Q9HC29 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24795947 0.98 ATM (0.39) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL21389261 0.88 ATM (0.50) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL24796649 0.85 ATM (0.46) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL24796295 0.85 ATM (0.49) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL24795923 0.84 L3MBTL1 (0.44) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL24795942 0.81 ATM (0.44) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL21389270 0.81 HPGD (0.44) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL24796401 0.79 HPGD (0.41) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL24796661 0.78 HPGD (0.43) ATMHPGDKMT2ALMNASMN1; SMN2
SCHEMBL24796282 0.76 HPGD (0.47) ATMHPGDKMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR ATM 4515/4885HPGD 2144/4885KMT2A 2741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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