Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283562 | 0.76 | — | — | |
| SCHEMBL13275995 | 0.76 | — | — | |
| SCHEMBL6126636 | 0.73 | GPR119 (0.38) | ADRA1AADRA2A | |
| SCHEMBL17363105 | 0.73 | HTR2B (0.45) | HTR2BADRA1AADRA2A | |
| SCHEMBL6126637 | 0.73 | GPR119 (0.38) | ADRA1AADRA2A | |
| SCHEMBL2476920 | 0.72 | — | — | |
| SCHEMBL10211001 | 0.72 | GPR119 (0.37) | — | |
| SCHEMBL17270437 | 0.71 | HPGDS (0.44) | — | |
| SCHEMBL15411793 | 0.71 | HPGDS (0.40) | — | |
| SCHEMBL1294318 | 0.70 | HTR2B (0.36) | HTR2BADRA1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575475-A1 | INHIBITORS OF HCV NS5A | Presidio Pharmaceuticals, Inc. (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011150243-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2011-12-01 | — | — | WO | disclosed |
| EP-2373167-A1 | INHIBITORS OF HCV NS5A | Presidio Pharmaceuticals, Inc. (US) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010065668-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |