Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541133 | 0.81 | MEN1 (0.63) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL5012749 | 0.79 | CHRNB4 (0.40) | MEN1KMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL4712782 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL6431088 | 0.78 | MEN1 (0.48) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL2917851 | 0.77 | L3MBTL1 (0.46) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL690539 | 0.77 | HTR2C (0.46) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4707711 | 0.77 | SMN1; SMN2 (0.53) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL5198237 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL541558 | 0.76 | MEN1 (0.57) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL4708973 | 0.74 | TSHR (0.49) | ALDH1A1MEN1KMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374806-B1 | OXAZOLIDINON-QUINOLONE HYBRIDES AND INTERMEDIATES FOR THEIR PREPARATION | MORPHOCHEM AG FÜR KOMBINATORISCHE CHEMIE (DE) | 2016-11-02 | — | — | EP | disclosed |
| EP-1660489-B1 | INTERMEDIATE PRODUCTS FOR PRODUCING OXAZOLIDINONE-QUINOLONE HYBRIDS | MORPHOCHEM AG FÜR KOMBINATORISCHE CHEMIE (DE) | 2014-07-02 | — | — | EP | disclosed |
| EP-2374806-A1 | OXAZOLIDINON-QUINOLONe HYBRIDes and intermediates for their preparation | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2011-10-12 | — | — | EP | disclosed |