Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758662 | 0.81 | ALDH1A1 (0.44) | TMEM97SIGMAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7606236 | 0.81 | MEN1 (0.48) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL7633589 | 0.80 | MEN1 (0.47) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL92564 | 0.80 | MEN1 (0.61) | TSHRTMEM97SIGMAR1MEN1KMT2A | |
| SCHEMBL21421643 | 0.80 | ALDH1A1 (0.52) | TSHRTMEM97SIGMAR1ALDH1A1MEN1 | |
| SCHEMBL690539 | 0.78 | HTR2C (0.46) | SIGMAR1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL2917851 | 0.78 | L3MBTL1 (0.46) | ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL4759021 | 0.77 | CYP2D6 (0.49) | TSHRALDH1A1GAA | |
| SCHEMBL21673734 | 0.77 | ALDH1A1 (0.48) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8549660 | 0.77 | ALDH1A1 (0.43) | TSHRALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |